![]() Ostomy Wound Manage 56:60–67īorgquist O, Gustafsson L, Ingemansson R, Malmsjo M (2010b) Micro- and macromechanical effects on the wound bed of negative pressure wound therapy using gauze and foam. Wounds 22:32–37īorgquist O, Ingemansson R, Malmsjo M (2010a) The effect of intermittent and variable negative pressure wound therapy on wound edge microvascular blood flow. īoone D, Braitman E, Gentics C, Afthinos J, Latif J, Sordillo E et al (2010) Bacterial burden and wound outcomes as influenced by negative pressure wound therapy. īoissiere F, Gandolfi S, Riot S, Kerfant N, Jenzeri A, Hendriks S et al (2021) Flap venous congestion and salvage techniques: a systematic literature review. ![]() īlackburn 2nd JH, Boemi L, Hall WW, Jeffords K, Hauck RM, Banducci DR et al (1998) Negative-pressure dressings as a bolster for skin grafts. ījarnason T, Montgomery A, Hlebowicz J, Lindstedt S, Petersson U (2011) Pressure at the bowel surface during topical negative pressure therapy of the open abdomen: an experimental study in a porcine model. īiermann N, Geissler EK, Brix E, Schiltz D, Muehle C, Prantl L et al (2020) Pressure distribution and flow characteristics during negative pressure wound therapy. īiermann N, Geissler EK, Brix E, Schiltz D, Prantl L, Kehrer A et al (2019) Oxygen levels during negative pressure wound therapy. īertelsen CA, Fabricius R, Kleif J, Kristensen B, Gogenur I (2014) Outcome of negative-pressure wound therapy for open abdomen treatment after nontraumatic lower gastrointestinal surgery: analysis of factors affecting delayed fascial closure in 101 patients. Īydin OE, Algan S, Tan O, Demirci E, Keles ON, Kantarci A (2019) A novel method for flap delay vacuum assisted flap delay: an experimental study in rabbits. ![]() Ann Plast Surg 38:563–576 discussion 577Īssadian O, Assadian A, Stadler M, Diab-Elschahawi M, Kramer A (2010) Bacterial growth kinetic without the influence of the immune system using vacuum-assisted closure dressing with and without negative pressure in an in vitro wound model. Īrgenta LC, Morykwas MJ (1997) Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Īnesater E, Borgquist O, Hedstrom E, Waga J, Ingemansson R, Malmsjo M (2011) The influence of different sizes and types of wound fillers on wound contraction and tissue pressure during negative pressure wound therapy. Ostomy Wound Manage 55:22–28Īlford PW, Nesmith AP, Seywerd JN, Grosberg A, Parker KK (2011) Vascular smooth muscle contractility depends on cell shape. Īhearn C (2009) Intermittent NPWT and lower negative pressures – exploring the disparity between science and current practice: a review. KeywordsĪbarca-Buis RF, Munguia NM, Gonzalez JM, Solis-Arrieta L, Osorio LS, Krotzsch E (2014) Silver from polyurethane dressing is delivered by gradient to exudate, tissue, and serum of patients undergoing negative-pressure wound treatment. This chapter will help the reader to understand the current status and shortcomings of NPWT-related research, which could aid in the development of basic research and, eventually, clinical use with stronger scientific evidence. Particularly, attention has shifted from the four main mechanisms of NPWT to the accompanying secondary effects, such as effects on various cells, bacteria, and surgical wounds. ![]() Here, we have summarized the history of NPWT, its mechanism of action, what is currently known about it, and what is expected to be known in the future. A quarter of a century after its introduction, NPWT has been used in various clinical conditions, although molecular biological evidence is insufficient due to delay in basic research. Negative-pressure wound therapy (NPWT) promotes wound healing by applying negative pressure to the wound surface.
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